The condition of your body.
How you hold yourself when you play.
How your body uses your metabolism.
The difficulty on which you play.
Do you hold on to the bar while playing?
How long do you play?

I’m a no-bar player who started late October 2004. I got serious about the game because I wanted to impress this girl that I wanted to be with… oh boy, I wanted it so much. During that time I became addicted to DDR and ended up losing 67 pounds in a little over a month and a half.

So I can say without a doubt, that you certainly CAN lose weight playing this game.